↑ GRCh38: Ensembl release 89: ENSG00000206073 - Ensembl, May 2017
"Human PubMed Reference:".
Schneider SS, Schick C, Fish KE, Miller E, Pena JC, Treter SD, Hui SM, Silverman GA (May 1995). "A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene". Proc Natl Acad Sci U S A. 92 (8): 3147–51. doi:10.1073/pnas.92.8.3147. PMC42122. PMID 7724531.
Sakata Y, Arima K, Takai T, Sakurai W, Masumoto K, Yuyama N, Suminami Y, Kishi F, Yamashita T, Kato T, Ogawa H, Fujimoto K, Matsuo Y, Sugita Y, Izuhara K (Feb 2004). "The squamous cell carcinoma antigen 2 inhibits the cysteine proteinase activity of a major mite allergen, Der p 1". J Biol Chem. 279 (7): 5081–7. doi:10.1074/jbc.M311585200. PMID 14630915.
"Entrez Gene: SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4".
แหล่งข้อมูลอื่น
Barnes RC, Worrall DM (1995). "Identification of a novel human serpin gene; cloning sequencing and expression of leupin". FEBS Letters. 373 (1): 61–5. doi:10.1016/0014-5793(95)01015-7. PMID 7589435. S2CID 26092255.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Bartuski AJ, Kamachi Y, Schick C, และคณะ (1999). "A murine ortholog of the human serpin SCCA2 maps to chromosome 1 and inhibits chymotrypsin-like serine proteinases". Genomics. 54 (2): 297–306. doi:10.1006/geno.1998.5586. PMID 9828132.
Sakaguchi Y, Kishi F, Murakami A, และคณะ (1999). "Structural analysis of human SCC antigen 2 promoter". Biochim. Biophys. Acta. 1444 (1): 111–6. doi:10.1016/s0167-4781(98)00259-0. PMID 9931463.
Cataltepe S, Gornstein ER, Schick C, และคณะ (2000). "Co-expression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissues and squamous cell carcinomas". J. Histochem. Cytochem. 48 (1): 113–22. doi:10.1177/002215540004800112. PMID 10653592.
Luke C, Schick C, Tsu C, และคณะ (2000). "Simple modifications of the serpin reactive site loop convert SCCA2 into a cysteine proteinase inhibitor: a critical role for the P3' proline in facilitating RSL cleavage". Biochemistry. 39 (24): 7081–91. doi:10.1021/bi000050g. PMID 10852705.
Uemura Y, Pak SC, Luke C, และคณะ (2000). "Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells". Int. J. Cancer. 89 (4): 368–77. doi:10.1002/1097-0215(20000720)89:4<368::AID-IJC9>3.0.CO;2-6. PMID 10956412.
Hamada K, Shinomiya H, Asano Y, และคณะ (2001). "Molecular cloning of human squamous cell carcinoma antigen 1 gene and characterization of its promoter". Biochim. Biophys. Acta. 1518 (1–2): 124–31. doi:10.1016/s0167-4781(01)00174-9. PMID 11267667.
Takeda A, Kajiya A, Iwasawa A, และคณะ (2003). "Aberrant expression of serpin squamous cell carcinoma antigen 2 in human tumor tissues and cell lines: evidence of protection from tumor necrosis factor-mediated apoptosis". Biol. Chem. 383 (7–8): 1231–6. doi:10.1515/BC.2002.136. PMID 12437110. S2CID 23972588.
Strausberg RL, Feingold EA, Grouse LH, และคณะ (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC139241. PMID 12477932.
Gariboldi M, Peissel B, Fabbri A, และคณะ (2003). "SCCA2-like serpins mediate genetic predisposition to skin tumors". Cancer Res. 63 (8): 1871–5. PMID 12702576.
Pontisso P, Calabrese F, Benvegnù L, และคณะ (2004). "Overexpression of squamous cell carcinoma antigen variants in hepatocellular carcinoma". Br. J. Cancer. 90 (4): 833–7. doi:10.1038/sj.bjc.6601543. PMC2410161. PMID 14970861.
Gerhard DS, Wagner L, Feingold EA, และคณะ (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC528928. PMID 15489334.
Ray R, Choi M, Zhang Z, และคณะ (2005). "Uteroglobin suppresses SCCA gene expression associated with allergic asthma". J. Biol. Chem. 280 (11): 9761–4. doi:10.1074/jbc.C400581200. PMID 15677460.
Rual JF, Venkatesan K, Hao T, และคณะ (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Kimura K, Wakamatsu A, Suzuki Y, และคณะ (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC1356129. PMID 16344560.
Katagiri C, Nakanishi J, Kadoya K, Hibino T (2006). "Serpin squamous cell carcinoma antigen inhibits UV-induced apoptosis via suppression of c-JUN NH2-terminal kinase". J. Cell Biol. 172 (7): 983–90. doi:10.1083/jcb.200508064. PMC2063756. PMID 16549498.
serpinb4, เซอร, งกฤษ, serpin, หร, squamous, cell, carcinoma, antigen, scca2, เป, นโปรต, นของมน, ษย, และเป, นโปรต, นสมาช, กลำด, บท, ในเคลดบ, ของมหาวงศ, เซอร, serpin, family, member, กถอดรห, สได, จากย, บนโครโมโซมค, identifiersaliases, leupin, pi11, scca, scca1, . esxrpin bi4 xngkvs Serpin B4 hrux SERPINB4 Squamous cell carcinoma antigen 2 SCCA2 epnoprtinkhxngmnusy aelaepnoprtinsmachikladbthi 4 inekhldbikhxngmhawngsesxrpin Serpin family B member 4 thukthxdrhsidcakyin SERPINB4 bnokhromosmkhuthi 18 3 4 5 SERPINB4IdentifiersAliasesSERPINB4 LEUPIN PI11 SCCA 2 SCCA1 SCCA2 serpin family B member 4External IDsOMIM 600518 HomoloGene 76659 GeneCards SERPINB4Gene location Human Chr Chromosome 18 human 1 Band18q21 33Start63 637 259 bp 1 End63 644 256 bp 1 Gene ontologyMolecular function peptidase inhibitor activity protease binding enzyme binding serine type endopeptidase inhibitor activityCellular component isothphlasum phayinesll phaynxkesllBiological process negative regulation of peptidase activity regulation of proteolysis protection from natural killer cell mediated cytotoxicity negative regulation of endopeptidase activitySources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez6318n aEnsemblENSG00000206073n aUniProtP48594n aRefSeq mRNA NM 002974NM 175041n aRefSeq protein NP 002965NP 778206n aLocation UCSC Chr 18 63 64 63 64 Mbn aPubMed search 2 n aWikidataView Edit Humanduephim aekikhesxrpinxangxing aekikh 1 0 1 1 1 2 GRCh38 Ensembl release 89 ENSG00000206073 Ensembl May 2017 Human PubMed Reference Schneider SS Schick C Fish KE Miller E Pena JC Treter SD Hui SM Silverman GA May 1995 A serine proteinase inhibitor locus at 18q21 3 contains a tandem duplication of the human squamous cell carcinoma antigen gene Proc Natl Acad Sci U S A 92 8 3147 51 doi 10 1073 pnas 92 8 3147 PMC 42122 PMID 7724531 Sakata Y Arima K Takai T Sakurai W Masumoto K Yuyama N Suminami Y Kishi F Yamashita T Kato T Ogawa H Fujimoto K Matsuo Y Sugita Y Izuhara K Feb 2004 The squamous cell carcinoma antigen 2 inhibits the cysteine proteinase activity of a major mite allergen Der p 1 J Biol Chem 279 7 5081 7 doi 10 1074 jbc M311585200 PMID 14630915 Entrez Gene SERPINB4 serpin peptidase inhibitor clade B ovalbumin member 4 aehlngkhxmulxun aekikhBarnes RC Worrall DM 1995 Identification of a novel human serpin gene cloning sequencing and expression of leupin FEBS Letters 373 1 61 5 doi 10 1016 0014 5793 95 01015 7 PMID 7589435 S2CID 26092255 Bonaldo MF Lennon G Soares MB 1997 Normalization and subtraction two approaches to facilitate gene discovery Genome Res 6 9 791 806 doi 10 1101 gr 6 9 791 PMID 8889548 Bartuski AJ Kamachi Y Schick C aelakhna 1999 A murine ortholog of the human serpin SCCA2 maps to chromosome 1 and inhibits chymotrypsin like serine proteinases Genomics 54 2 297 306 doi 10 1006 geno 1998 5586 PMID 9828132 Sakaguchi Y Kishi F Murakami A aelakhna 1999 Structural analysis of human SCC antigen 2 promoter Biochim Biophys Acta 1444 1 111 6 doi 10 1016 s0167 4781 98 00259 0 PMID 9931463 Cataltepe S Gornstein ER Schick C aelakhna 2000 Co expression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissues and squamous cell carcinomas J Histochem Cytochem 48 1 113 22 doi 10 1177 002215540004800112 PMID 10653592 Luke C Schick C Tsu C aelakhna 2000 Simple modifications of the serpin reactive site loop convert SCCA2 into a cysteine proteinase inhibitor a critical role for the P3 proline in facilitating RSL cleavage Biochemistry 39 24 7081 91 doi 10 1021 bi000050g PMID 10852705 Uemura Y Pak SC Luke C aelakhna 2000 Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells Int J Cancer 89 4 368 77 doi 10 1002 1097 0215 20000720 89 4 lt 368 AID IJC9 gt 3 0 CO 2 6 PMID 10956412 Hamada K Shinomiya H Asano Y aelakhna 2001 Molecular cloning of human squamous cell carcinoma antigen 1 gene and characterization of its promoter Biochim Biophys Acta 1518 1 2 124 31 doi 10 1016 s0167 4781 01 00174 9 PMID 11267667 Takeda A Kajiya A Iwasawa A aelakhna 2003 Aberrant expression of serpin squamous cell carcinoma antigen 2 in human tumor tissues and cell lines evidence of protection from tumor necrosis factor mediated apoptosis Biol Chem 383 7 8 1231 6 doi 10 1515 BC 2002 136 PMID 12437110 S2CID 23972588 Strausberg RL Feingold EA Grouse LH aelakhna 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Gariboldi M Peissel B Fabbri A aelakhna 2003 SCCA2 like serpins mediate genetic predisposition to skin tumors Cancer Res 63 8 1871 5 PMID 12702576 Pontisso P Calabrese F Benvegnu L aelakhna 2004 Overexpression of squamous cell carcinoma antigen variants in hepatocellular carcinoma Br J Cancer 90 4 833 7 doi 10 1038 sj bjc 6601543 PMC 2410161 PMID 14970861 Gerhard DS Wagner L Feingold EA aelakhna 2004 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Ray R Choi M Zhang Z aelakhna 2005 Uteroglobin suppresses SCCA gene expression associated with allergic asthma J Biol Chem 280 11 9761 4 doi 10 1074 jbc C400581200 PMID 15677460 Rual JF Venkatesan K Hao T aelakhna 2005 Towards a proteome scale map of the human protein protein interaction network Nature 437 7062 1173 8 doi 10 1038 nature04209 PMID 16189514 S2CID 4427026 Sueoka K Nawata S Nakagawa T aelakhna 2005 Tumor associated serpin squamous cell carcinoma antigen stimulates matrix metalloproteinase 9 production in cervical squamous cell carcinoma cell lines Int J Oncol 27 5 1345 53 doi 10 3892 ijo 27 5 1345 PMID 16211231 Kimura K Wakamatsu A Suzuki Y aelakhna 2006 Diversification of transcriptional modulation large scale identification and characterization of putative alternative promoters of human genes Genome Research 16 1 55 65 doi 10 1101 gr 4039406 PMC 1356129 PMID 16344560 Katagiri C Nakanishi J Kadoya K Hibino T 2006 Serpin squamous cell carcinoma antigen inhibits UV induced apoptosis via suppression of c JUN NH2 terminal kinase J Cell Biol 172 7 983 90 doi 10 1083 jcb 200508064 PMC 2063756 PMID 16549498 thankhxmulxxniln MEROPS sahrbeppthieds aelasarybyngeppthieds I04 009 SERPINB4 protein human inhxsmudaephthysastraehngchatixemrikn sahrbhwkhxenuxhathangkaraephthy MeSH bthkhwamniekiywkhxngkbyinbnokhromosmkhuthi 18 aelaepnbthkhwamthikalngrxephimetimkhxmul khunsamarthchwyephimetimkhxmulinswnniidekhathungcak https th wikipedia org w index php title SERPINB4 amp oldid 9088867, wikipedia, วิกิ หนังสือ, หนังสือ, ห้องสมุด,
