↑ GRCh38: Ensembl release 89: ENSG00000021355 - Ensembl, May 2017
"Human PubMed Reference:".
Remold-O'Donnell E, Chin J, Alberts M (Jul 1992). "Sequence and molecular characterization of human monocyte/neutrophil elastase inhibitor". Proc Natl Acad Sci U S A. 89 (12): 5635–9. Bibcode:1992PNAS...89.5635R. doi:10.1073/pnas.89.12.5635. PMC49347. PMID 1376927.
"Entrez Gene: SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1".
↑ Benarafa C, Remold-O'Donnell E (August 2005). "The ovalbumin serpins revisited: perspective from the chicken genome of clade B serpin evolution in vertebrates". Proc. Natl. Acad. Sci. U.S.A. 102 (32): 11367–72. Bibcode:2005PNAS..10211367B. doi:10.1073/pnas.0502934102. PMC1183561. PMID 16055559.
Gong D, Farley K, White M, Hartshorn KL, Benarafa C, Remold-O'Donnell E (August 2011). "Critical role of serpinB1 in regulating inflammatory responses in pulmonary influenza infection". J. Infect. Dis. 204 (4): 592–600. doi:10.1093/infdis/jir352. PMC3144176. PMID 21791661.
Benarafa C, LeCuyer TE, Baumann M, Stolley JM, Cremona TP, Remold-O'Donnell E (July 2011). "SerpinB1 protects the mature neutrophil reserve in the bone marrow". J. Leukoc. Biol. 90 (1): 21–9. doi:10.1189/jlb.0810461. PMC3114599. PMID 21248149.
Benarafa C, Priebe GP, Remold-O'Donnell E (August 2007). "The neutrophil serine protease inhibitor serpinb1 preserves lung defense functions in Pseudomonas aeruginosa infection". J. Exp. Med. 204 (8): 1901–9. doi:10.1084/jem.20070494. PMC2118684. PMID 17664292.
แหล่งข้อมูลอื่น
Rasmussen HH, van Damme J, Puype M, และคณะ (1993). "Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes". Electrophoresis. 13 (12): 960–9. doi:10.1002/elps.11501301199. PMID 1286667. S2CID 41855774.
Packard BZ, Lee SS, Remold-O'Donnell E, Komoriya A (1995). "A serpin from human tumor cells with direct lymphoid immunomodulatory activity: mitogenic stimulation of human tumor-infiltrating lymphocytes". Biochim. Biophys. Acta. 1269 (1): 41–50. doi:10.1016/0167-4889(95)00113-7. PMID 7578269.
Sugimori T, Cooley J, Hoidal JR, Remold-O'Donnell E (1995). "Inhibitory properties of recombinant human monocyte/neutrophil elastase inhibitor". Am. J. Respir. Cell Mol. Biol. 13 (3): 314–22. doi:10.1165/ajrcmb.13.3.7654387. PMID 7654387.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Evans E, Cooley J, Remold-O'Donnell E (1996). "Characterization and chromosomal localization of ELANH2, the gene encoding human monocyte/neutrophil elastase inhibitor". Genomics. 28 (2): 235–40. doi:10.1006/geno.1995.1136. PMID 8530031.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, และคณะ (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Zeng W, Silverman GA, Remold-O'Donnell E (1998). "Structure and sequence of human M/NEI (monocyte/neutrophil elastase inhibitor), an Ov-serpin family gene". Gene. 213 (1–2): 179–87. doi:10.1016/S0378-1119(98)00189-9. PMID 9630619.
Sun J, Stephens R, Mirza G, และคณะ (1999). "A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes". Cytogenet. Cell Genet. 82 (3–4): 273–7. doi:10.1159/000015118. PMID 9858835. S2CID 23659776.
Perani P, Zeggai S, Torriglia A, Courtois Y (2000). "Mutations on the hinge region of leukocyte elastase inhibitor determine the loss of inhibitory function". Biochem. Biophys. Res. Commun. 274 (3): 841–4. doi:10.1006/bbrc.2000.3191. PMID 10924364.
Cooley J, Takayama TK, Shapiro SD, และคณะ (2002). "The serpin MNEI inhibits elastase-like and chymotrypsin-like serine proteases through efficient reactions at two active sites". Biochemistry. 40 (51): 15762–70. doi:10.1021/bi0113925. PMID 11747453.
Korkmaz B, Attucci S, Hazouard E, และคณะ (2002). "Discriminating between the activities of human neutrophil elastase and proteinase 3 using serpin-derived fluorogenic substrates". J. Biol. Chem. 277 (42): 39074–81. doi:10.1074/jbc.M202918200. PMID 12114510.
Benarafa C, Cooley J, Zeng W, และคณะ (2003). "Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1)". J. Biol. Chem. 277 (44): 42028–33. doi:10.1074/jbc.M207080200. PMID 12189154.
Strausberg RL, Feingold EA, Grouse LH, และคณะ (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC139241. PMID 12477932.
Gevaert K, Goethals M, Martens L, และคณะ (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801. S2CID 23783563.
Mungall AJ, Palmer SA, Sims SK, และคณะ (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Gerhard DS, Wagner L, Feingold EA, และคณะ (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC528928. PMID 15489334.
Ahmed M, Forsberg J, Bergsten P (2005). "Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry". J. Proteome Res. 4 (3): 931–40. doi:10.1021/pr050024a. PMID 15952740.
serpinb1, วโคไซต, ลาสเตสอ, นฮ, เตอร, หร, เซอร, งกฤษ, leukocyte, elastase, inhibitor, หร, serpin, เป, นโปรต, นท, พบในมน, ษย, กถอดรห, สได, จากย, บนโครโมโซมค, และจ, ดเป, นสมาช, กลำด, บท, ในเคลดบ, โอแวลบ, ของมหาวงศ, เซอร, available, structurespdbhuman, uniprot, se. liwokhist xilasetsxinhibietxr hrux esxrpin bi1 xngkvs Leukocyte elastase inhibitor LEI hrux serpin B1 epnoprtinthiphbinmnusythithukthxdrhsidcakyin SERPINB1 bnokhromosmkhuthi 6 aelacdepnsmachikladbthi 1 inekhldbi oxaewlbumin khxngmhawngsesxrpin 3 4 5 SERPINB1Available structuresPDBHuman UniProt search PDBe RCSBList of PDB id codes4GA7IdentifiersAliasesSERPINB1 EI ELANH2 HEL57 LEI M NEI MNEI PI 2 PI2 HEL S 27 serpin family B member 1External IDsOMIM 130135 HomoloGene 133768 GeneCards SERPINB1Gene location Human Chr Chromosome 6 human 1 Band6p25 2Start2 832 332 bp 1 End2 841 959 bp 1 RNA expression patternMore reference expression dataGene ontologyMolecular function peptidase inhibitor activity serine type endopeptidase inhibitor activity GO 0001948 karcbkboprtinCellular component isothphlasum exkososmchnidphaynxkesll eyuxhum phaynxkesll secretory granule lumen GO 0005578 sarekhluxbesll extracellular region sarekhluxbesllthimikhxllaecnepnswnprakxbBiological process negative regulation of peptidase activity negative regulation of endopeptidase activity neutrophil degranulation type B pancreatic cell proliferationSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez1992n aEnsemblENSG00000021355n aUniProtP30740n aRefSeq mRNA NM 030666n aRefSeq protein NP 109591n aLocation UCSC Chr 6 2 83 2 84 Mbn aPubMed search 2 n aWikidataView Edit HumanLEI khxngmnusymi Ortholog thiphbinhnu khux omonist niwotrfil xilasetsxinhibietxr monocyte neutrophil elastase inhibitor MNEI 5 enuxha 1 hnathi 2 duephim 3 xangxing 4 aehlngkhxmulxunhnathi aekikhliwokhist xilasetsxinhibietxrcdepnsartansirinoprtiexs serine protease inhibitor cakniwotrfilthiphbidinisothphlasum emuxepriybethiybkbsirinoprtiexsaetlachnidaelwphbwa LEI camivththiybyngthicaephaatx niwothrfilxilasets PR3 aela khaethphsin ci sungoprtiexsthng 3 chnidnilwnphbidthwipinaekrnulkhxngniwotrfil thngni cakkarsuksaphbwa LEI thahnathichwyldkarbadecbkhxngenuxeyuxthixacekidkhunidrahwangkrabwnkarxkesb sungepnphlmacakexnismsirinoprtiexskhangtn aelayngmibthbathsakhytxphawatharngdulkhxngniwotrfilinhnuimsdwy nxkcakni karsuksainstwthdlxngthitidechux echn pxdxkesb phbwa mikhwamsmphnthuknrahwangkarkhad LEI kbkhwamsamarthinkarkacdechuxculchiphkhxngenuxeyuxthitidechuxnn cungxacphxxnumanidwa LEI mibthbathsakhyinkartanechuxculchiphinstwthdlxngdngklaw 6 7 8 duephim aekikhesxrpinxangxing aekikh 1 0 1 1 1 2 GRCh38 Ensembl release 89 ENSG00000021355 Ensembl May 2017 Human PubMed Reference Remold O Donnell E Chin J Alberts M Jul 1992 Sequence and molecular characterization of human monocyte neutrophil elastase inhibitor Proc Natl Acad Sci U S A 89 12 5635 9 Bibcode 1992PNAS 89 5635R doi 10 1073 pnas 89 12 5635 PMC 49347 PMID 1376927 Entrez Gene SERPINB1 serpin peptidase inhibitor clade B ovalbumin member 1 5 0 5 1 Benarafa C Remold O Donnell E August 2005 The ovalbumin serpins revisited perspective from the chicken genome of clade B serpin evolution in vertebrates Proc Natl Acad Sci U S A 102 32 11367 72 Bibcode 2005PNAS 10211367B doi 10 1073 pnas 0502934102 PMC 1183561 PMID 16055559 Gong D Farley K White M Hartshorn KL Benarafa C Remold O Donnell E August 2011 Critical role of serpinB1 in regulating inflammatory responses in pulmonary influenza infection J Infect Dis 204 4 592 600 doi 10 1093 infdis jir352 PMC 3144176 PMID 21791661 Benarafa C LeCuyer TE Baumann M Stolley JM Cremona TP Remold O Donnell E July 2011 SerpinB1 protects the mature neutrophil reserve in the bone marrow J Leukoc Biol 90 1 21 9 doi 10 1189 jlb 0810461 PMC 3114599 PMID 21248149 Benarafa C Priebe GP Remold O Donnell E August 2007 The neutrophil serine protease inhibitor serpinb1 preserves lung defense functions in Pseudomonas aeruginosa infection J Exp Med 204 8 1901 9 doi 10 1084 jem 20070494 PMC 2118684 PMID 17664292 aehlngkhxmulxun aekikhRasmussen HH van Damme J Puype M aelakhna 1993 Microsequences of 145 proteins recorded in the two dimensional gel protein database of normal human epidermal keratinocytes Electrophoresis 13 12 960 9 doi 10 1002 elps 11501301199 PMID 1286667 S2CID 41855774 Packard BZ Lee SS Remold O Donnell E Komoriya A 1995 A serpin from human tumor cells with direct lymphoid immunomodulatory activity mitogenic stimulation of human tumor infiltrating lymphocytes Biochim Biophys Acta 1269 1 41 50 doi 10 1016 0167 4889 95 00113 7 PMID 7578269 Sugimori T Cooley J Hoidal JR Remold O Donnell E 1995 Inhibitory properties of recombinant human monocyte neutrophil elastase inhibitor Am J Respir Cell Mol Biol 13 3 314 22 doi 10 1165 ajrcmb 13 3 7654387 PMID 7654387 Maruyama K Sugano S 1994 Oligo capping a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides Gene 138 1 2 171 4 doi 10 1016 0378 1119 94 90802 8 PMID 8125298 Evans E Cooley J Remold O Donnell E 1996 Characterization and chromosomal localization of ELANH2 the gene encoding human monocyte neutrophil elastase inhibitor Genomics 28 2 235 40 doi 10 1006 geno 1995 1136 PMID 8530031 Suzuki Y Yoshitomo Nakagawa K Maruyama K aelakhna 1997 Construction and characterization of a full length enriched and a 5 end enriched cDNA library Gene 200 1 2 149 56 doi 10 1016 S0378 1119 97 00411 3 PMID 9373149 Zeng W Silverman GA Remold O Donnell E 1998 Structure and sequence of human M NEI monocyte neutrophil elastase inhibitor an Ov serpin family gene Gene 213 1 2 179 87 doi 10 1016 S0378 1119 98 00189 9 PMID 9630619 Sun J Stephens R Mirza G aelakhna 1999 A serpin gene cluster on human chromosome 6p25 contains PI6 PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes Cytogenet Cell Genet 82 3 4 273 7 doi 10 1159 000015118 PMID 9858835 S2CID 23659776 Perani P Zeggai S Torriglia A Courtois Y 2000 Mutations on the hinge region of leukocyte elastase inhibitor determine the loss of inhibitory function Biochem Biophys Res Commun 274 3 841 4 doi 10 1006 bbrc 2000 3191 PMID 10924364 Cooley J Takayama TK Shapiro SD aelakhna 2002 The serpin MNEI inhibits elastase like and chymotrypsin like serine proteases through efficient reactions at two active sites Biochemistry 40 51 15762 70 doi 10 1021 bi0113925 PMID 11747453 Korkmaz B Attucci S Hazouard E aelakhna 2002 Discriminating between the activities of human neutrophil elastase and proteinase 3 using serpin derived fluorogenic substrates J Biol Chem 277 42 39074 81 doi 10 1074 jbc M202918200 PMID 12114510 Benarafa C Cooley J Zeng W aelakhna 2003 Characterization of four murine homologs of the human ov serpin monocyte neutrophil elastase inhibitor MNEI SERPINB1 J Biol Chem 277 44 42028 33 doi 10 1074 jbc M207080200 PMID 12189154 Strausberg RL Feingold EA Grouse LH aelakhna 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Gevaert K Goethals M Martens L aelakhna 2004 Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N terminal peptides Nat Biotechnol 21 5 566 9 doi 10 1038 nbt810 PMID 12665801 S2CID 23783563 Mungall AJ Palmer SA Sims SK aelakhna 2003 The DNA sequence and analysis of human chromosome 6 Nature 425 6960 805 11 Bibcode 2003Natur 425 805M doi 10 1038 nature02055 PMID 14574404 Gerhard DS Wagner L Feingold EA aelakhna 2004 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Ahmed M Forsberg J Bergsten P 2005 Protein profiling of human pancreatic islets by two dimensional gel electrophoresis and mass spectrometry J Proteome Res 4 3 931 40 doi 10 1021 pr050024a PMID 15952740 thankhxmulxxniln MEROPS sahrbeppthieds aelasarybyngeppthieds I04 006 SERPINB1 protein human inhxsmudaephthysastraehngchatixemrikn sahrbhwkhxenuxhathangkaraephthy MeSH bthkhwamnirwbrwmkhxmulcakhxsmudaephthysastraehngchatixemrikn sungcdepnsatharnsmbti bthkhwamekiywkhxngkbyinbnokhromosmkhuthi 6 niyngepnokhrng khunsamarthchwywikiphiediyidodykarephimetimkhxmul ekhathungcak https th wikipedia org w index php title SERPINB1 amp oldid 9108742, wikipedia, วิกิ หนังสือ, หนังสือ, ห้องสมุด,
