• unfolded protein binding • chaperone binding • GO:0001948 การจับกับโปรตีน • ATP binding • heat shock protein binding • metal ion binding • ATPase activator activity
Cellular component
• เอกโซโซมชนิดภายนอกเซลล์ • เยื่อหุ้ม • ไซโตซอล
Biological process
• response to heat • การม้วนพับโปรตีน • protein refolding • positive regulation of cell population proliferation • positive regulation of ATPase activity
↑ GRCh38: Ensembl release 89: ENSG00000069345 - Ensembl, May 2017
"Human PubMed Reference:".
Lorain S, Quivy JP, Monier-Gavelle F, Scamps C, Lecluse Y, Almouzni G, Lipinski M (Sep 1998). "Core histones and HIRIP3, a novel histone-binding protein, directly interact with WD repeat protein HIRA". Mol Cell Biol. 18 (9): 5546–56. doi:10.1128/MCB.18.9.5546. PMC109139. PMID 9710638.
Ohtsuka K, Hata M (Jan 2001). "Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature". Cell Stress Chaperones. 5 (2): 98–112. doi:10.1379/1466-1268(2000)005<0098:MHDHCO>2.0.CO;2. ISSN 1466-1268. PMC312896. PMID 11147971.
↑ "Entrez Gene: DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2".
แหล่งข้อมูลอื่น
Bonwaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Edwards MC, Liegeois N, Horecka J, และคณะ (1998). "Human CPR (cell cycle progression restoration) genes impart a Far- phenotype on yeast cells". Genetics. 147 (3): 1063–76. PMC1208234. PMID 9383053.
Scanlan MJ, Gordan JD, Williamson B, และคณะ (1999). "Antigens recognized by autologous antibody in patients with renal-cell carcinoma". Int. J. Cancer. 83 (4): 456–64. doi:10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5. PMID 10508479.
Diefenbach J, Kindl H (2000). "The membrane-bound DnaJ protein located at the cytosolic site of glyoxysomes specifically binds the cytosolic isoform 1 of Hsp70 but not other Hsp70 species". Eur. J. Biochem. 267 (3): 746–54. doi:10.1046/j.1432-1327.2000.01053.x. PMID 10651811.
Terada K, Mori M (2000). "Human DnaJ homologs dj2 and dj3, and bag-1 are positive cochaperones of hsc70". J. Biol. Chem. 275 (32): 24728–34. doi:10.1074/jbc.M002021200. PMID 10816573.
Strausberg RL, Feingold EA, Grouse LH, และคณะ (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC139241. PMID 12477932.
Willingham S, Outeiro TF, DeVit MJ, และคณะ (2003). "Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein". Science. 302 (5651): 1769–72. doi:10.1126/science.1090389. PMID 14657499. S2CID 43221047.
Kho Y, Kim SC, Jiang C, และคณะ (2004). "A tagging-via-substrate technology for detection and proteomics of farnesylated proteins". Proc. Natl. Acad. Sci. U.S.A. 101 (34): 12479–84. doi:10.1073/pnas.0403413101. PMC515085. PMID 15308774.
Gerhard DS, Wagner L, Feingold EA, และคณะ (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC528928. PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, และคณะ (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC1356129. PMID 16344560.
Olsen JV, Blagoev B, Gnad F, และคณะ (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
dnaja2, บทความน, อเป, นภาษาอ, งกฤษ, เน, องจากย, งไม, อภาษาไทยท, กระช, เหมาะสม, ไม, ปรากฏคำอ, านท, แน, หร, อไม, ปรากฏคำแปลท, ใช, ในทางว, ชาการ, หร, dnaj, homolog, subfamily, member, หร, hirip4, เป, นโปรต, นท, พบในม, นษย, งถ, กถอดรห, สได, จากย, บนโครโมโซมค, hiri. bthkhwamnimichuxepnphasaxngkvs enuxngcakyngimmichuxphasaithythikrachb ehmaasm impraktkhaxanthiaenchd hruximpraktkhaaeplthiichinthangwichakarDNAJA2 hrux DnaJ homolog subfamily A member 2 hrux HIRIP4 epnoprtinthiphbinmunsy sungthukthxdrhsidcakyin DNAJA2 bnokhromosmkhuthi 16 3 4 5 HIRIP4 mikareriyngladbkrdxamionkhlaykb Hir1p aela Hir2p sungepntwybyngrwm corepressor inkrabwnkarthxdrhsoprtinhisotninyist Saccharomyces cerevisiae aelakhwamkhlaykhlungknxyangmak homologous kboprtinthiphlitidcakyin DNJ3 CPR3 khxngmnusy yin Dj3 khxnghnuthimithungnadi mouse aelayin Dj2 khxnghnuthiimmithungnadi rat 5 DNAJA2IdentifiersAliasesDNAJA2 CPR3 DJ3 DJA2 DNAJ DNJ3 HIRIP4 PRO3015 RDJ2 DnaJ heat shock protein family Hsp40 member A2External IDsOMIM 611322 HomoloGene 21193 GeneCards DNAJA2Gene location Human Chr Chromosome 16 human 1 Band16q11 2Start46 955 362 bp 1 End46 973 674 bp 1 RNA expression patternMore reference expression dataGene ontologyMolecular function unfolded protein binding chaperone binding GO 0001948 karcbkboprtin ATP binding heat shock protein binding metal ion binding ATPase activator activityCellular component exkososmchnidphaynxkesll eyuxhum isotsxlBiological process response to heat karmwnphboprtin protein refolding positive regulation of cell population proliferation positive regulation of ATPase activitySources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez10294n aEnsemblENSG00000069345n aUniProtO60884n aRefSeq mRNA NM 005880n aRefSeq protein NP 005871n aLocation UCSC Chr 16 46 96 46 97 Mbn aPubMed search 2 n aWikidataView Edit Humanthngni cakkhxmulkhunsmbtithangokhrngsrangkhxng HIRIP4 thaihphxkhadedaiwwa oprtinchnidnixacthahnathiepnswnprakxbhnungkhxngsarprakxboprtinechingsxnchnidxun cakkarsuksathdlxngthiphanma mikarkhnphb cDNA hlaychnid ody HIRIP thuxepnhnunginoprtinehlann sungsamarthaeyk HIRIP4 xxkmaidodyxasykarekidxntrkiriyakboprtinechingsxndngklaw xyangirktam cakkhxmulthimiinpccubn yngimephiyngphxthicarabuhnathithiaenchdkhxng HIRIP4 id 5 ladbkrdxamion1020304050MANVADTKLYDILGVPPGASENELKKAYRKLAKEYHPDKNPNAGDKFKEISFAYEVLSNPEKRELYDRYGEQGLREGSGGGGGMDDIFSHIFGGGLFGFMGNQSRSRNGRRRGEDMMHPLKVSLEDLYNGKTTKLQLSKNVLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDGRQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSRPEVPNIIGETEEVELQEFDSTRGSGGGQRREAYNDSSDEESSSHHGPGVQCAHQA xalanin C sistixin D krdaexspartik E klutaemt F finilxalanin G iklsin H histhidin I ixosliwsin K ilsin L liwsin M miithoxnin N aexspharacin P ophrlin Q klutamin R xarcinin S sirin T thrioxnin V walin W thripotefn Y ithorsinxangxing aekikh 1 0 1 1 1 2 GRCh38 Ensembl release 89 ENSG00000069345 Ensembl May 2017 Human PubMed Reference Lorain S Quivy JP Monier Gavelle F Scamps C Lecluse Y Almouzni G Lipinski M Sep 1998 Core histones and HIRIP3 a novel histone binding protein directly interact with WD repeat protein HIRA Mol Cell Biol 18 9 5546 56 doi 10 1128 MCB 18 9 5546 PMC 109139 PMID 9710638 Ohtsuka K Hata M Jan 2001 Mammalian HSP40 DNAJ homologs cloning of novel cDNAs and a proposal for their classification and nomenclature Cell Stress Chaperones 5 2 98 112 doi 10 1379 1466 1268 2000 005 lt 0098 MHDHCO gt 2 0 CO 2 ISSN 1466 1268 PMC 312896 PMID 11147971 5 0 5 1 5 2 Entrez Gene DNAJA2 DnaJ Hsp40 homolog subfamily A member 2 aehlngkhxmulxun aekikhBonwaldo MF Lennon G Soares MB 1997 Normalization and subtraction two approaches to facilitate gene discovery Genome Res 6 9 791 806 doi 10 1101 gr 6 9 791 PMID 8889548 Edwards MC Liegeois N Horecka J aelakhna 1998 Human CPR cell cycle progression restoration genes impart a Far phenotype on yeast cells Genetics 147 3 1063 76 PMC 1208234 PMID 9383053 Scanlan MJ Gordan JD Williamson B aelakhna 1999 Antigens recognized by autologous antibody in patients with renal cell carcinoma Int J Cancer 83 4 456 64 doi 10 1002 SICI 1097 0215 19991112 83 4 lt 456 AID IJC4 gt 3 0 CO 2 5 PMID 10508479 Diefenbach J Kindl H 2000 The membrane bound DnaJ protein located at the cytosolic site of glyoxysomes specifically binds the cytosolic isoform 1 of Hsp70 but not other Hsp70 species Eur J Biochem 267 3 746 54 doi 10 1046 j 1432 1327 2000 01053 x PMID 10651811 Terada K Mori M 2000 Human DnaJ homologs dj2 and dj3 and bag 1 are positive cochaperones of hsc70 J Biol Chem 275 32 24728 34 doi 10 1074 jbc M002021200 PMID 10816573 Strausberg RL Feingold EA Grouse LH aelakhna 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Willingham S Outeiro TF DeVit MJ aelakhna 2003 Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha synuclein Science 302 5651 1769 72 doi 10 1126 science 1090389 PMID 14657499 S2CID 43221047 Kho Y Kim SC Jiang C aelakhna 2004 A tagging via substrate technology for detection and proteomics of farnesylated proteins Proc Natl Acad Sci U S A 101 34 12479 84 doi 10 1073 pnas 0403413101 PMC 515085 PMID 15308774 Gerhard DS Wagner L Feingold EA aelakhna 2004 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Kimura K Wakamatsu A Suzuki Y aelakhna 2006 Diversification of transcriptional modulation large scale identification and characterization of putative alternative promoters of human genes Genome Res 16 1 55 65 doi 10 1101 gr 4039406 PMC 1356129 PMID 16344560 Olsen JV Blagoev B Gnad F aelakhna 2006 Global in vivo and site specific phosphorylation dynamics in signaling networks Cell 127 3 635 48 doi 10 1016 j cell 2006 09 026 PMID 17081983 S2CID 7827573 taaehnngyin DNAJA2 khxngmnusy in UCSC Genome Browser hnaephcaesdngraylaexiydekiywkbyin DNAJA2 khxngmnusy in UCSC Genome Browser bthkhwamniekiywkhxngkbyinbnokhromosmkhuthi 16 aelaepnbthkhwamthikalngrxephimetimkhxmul khunsamarthchwyephimetimkhxmulinswnniid ekhathungcak https th wikipedia org w index php title DNAJA2 amp oldid 9114741, wikipedia, วิกิ หนังสือ, หนังสือ, ห้องสมุด,
