• iron ion binding • oxygen binding • arachidonic acid epoxygenase activity • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen • metal ion binding • monooxygenase activity • heme binding • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen • oxidoreductase activity • aromatase activity • steroid hydroxylase activity
• epoxygenase P450 pathway • trichloroethylene metabolic process • xenobiotic metabolic process • response to toxic substance • organic acid metabolic process • exogenous drug catabolic process
National Center for Biotechnology Information (March 29, 2018). . U.S. National Library of Medicine. คลังข้อมูลเก่า เก็บจาก แหล่งเดิม เมื่อ October 9, 2017. สืบค้นเมื่อ April 11, 2018.
Nhamburo PT, Kimura S, McBride OW และคณะ (1990). "The human CYP2F gene subfamily: identification of a cDNA encoding a new cytochrome P450, cDNA-directed expression, and chromosome mapping". Biochemistry. 29 (23): 5491–9. doi:10.1021/bi00475a012. PMID 1974816.CS1 maint: uses authors parameter (link)
Bale AE, Mitchell AL, Gonzalez FJ, McBride OW (1991). "Localization of CYP2F1 by multipoint linkage analysis and pulsed-field gel electrophoresis". Genomics. 10 (1): 284–6. doi:10.1016/0888-7543(91)90514-F. PMID 2045106.CS1 maint: uses authors parameter (link)
Trask B, Fertitta A, Christensen M และคณะ (1993). "Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers". Genomics. 15 (1): 133–45. doi:10.1006/geno.1993.1021. PMID 8432525.CS1 maint: uses authors parameter (link)
Hoffman SM, Fernandez-Salguero P, Gonzalez FJ, Mohrenweiser HW (1996). "Organization and evolution of the cytochrome P450 CYP2A-2B-2F subfamily gene cluster on human chromosome 19". J. Mol. Evol. 41 (6): 894–900. doi:10.1007/bf00173169. PMID 8587134.CS1 maint: uses authors parameter (link)
Hakkola J, Pasanen M, Hukkanen J และคณะ (1996). "Expression of xenobiotic-metabolizing cytochrome P450 forms in human full-term placenta". Biochem. Pharmacol. 51 (4): 403–11. doi:10.1016/0006-2952(95)02184-1. PMID 8619884.CS1 maint: uses authors parameter (link)
Andersen MR, Farin FM, Omiecinski CJ (1998). "Quantification of multiple human cytochrome P450 mRNA molecules using competitive reverse transcriptase-PCR". DNA Cell Biol. 17 (3): 231–8. doi:10.1089/dna.1998.17.231. PMID 9539103.CS1 maint: uses authors parameter (link)
Lanza DL, Code E, Crespi CL และคณะ (1999). "Specific dehydrogenation of 3-methylindole and epoxidation of naphthalene by recombinant human CYP2F1 expressed in lymphoblastoid cells". Drug Metab. Dispos. 27 (7): 798–803. PMID 10383923.CS1 maint: uses authors parameter (link)
Chen N, Whitehead SE, Caillat AW และคณะ (2002). "Identification and cross-species comparisons of CYP2F subfamily genes in mammals". Mutat. Res. 499 (2): 155–61. doi:10.1016/S0027-5107(01)00274-3. PMID 11827709.CS1 maint: uses authors parameter (link)
Strausberg RL, Feingold EA, Grouse LH และคณะ (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC139241. PMID 12477932.CS1 maint: uses authors parameter (link)
Carr BA, Wan J, Hines RN, Yost GS (2003). "Characterization of the human lung CYP2F1 gene and identification of a novel lung-specific binding motif". J. Biol. Chem. 278 (18): 15473–83. doi:10.1074/jbc.M300319200. PMID 12598524.CS1 maint: uses authors parameter (link)
Tournel G, Cauffiez C, Billaut-Laden I และคณะ (2007). "Molecular analysis of the CYP2F1 gene: identification of a frequent non-functional allelic variant". Mutat. Res. 617 (1–2): 79–89. doi:10.1016/j.mrfmmm.2007.01.007. PMID 17327131.CS1 maint: uses authors parameter (link)
cyp2f1, ไซโทโครม, p450, งกฤษ, cytochrome, p450, อย, เป, นสมาช, กพอล, เปปไทด, ลำด, บท, ในสก, ลย, อย, ของสก, ลท, ในมหาสก, ลไซโทโครม, p450, ดเป, นโปรต, นอ, กชน, ดหน, งท, ณสมบ, เป, นเอนไซม, โดยม, เป, นต, วควบค, มการแสดงออก, งย, นน, เป, นส, วนหน, งของกล, มย, cytoch. isothokhrm P450 2F1 xngkvs Cytochrome P450 2F1 chuxyx CYP2F1 EC 1 14 14 1 epnsmachikphxlieppithdladbthi 1 inskulyxy F khxngskulthi 2 inmhaskulisothokhrm P450 cdepnoprtinxikchnidhnungthimikhunsmbtiepnexnismodymiyin CYP2F1 epntwkhwbkhumkaraesdngxxk 3 sungyinniepnswnhnungkhxngklumyin cytochrome P450 bn okhromosmkhuthi 19 olkhs 19q13 2 4 CYP2F1IdentifiersAliasesCYP2F1 C2F1 CYP2F CYPIIF1 cytochrome P450 family 2 subfamily F member 1External IDsOMIM 124070 HomoloGene 73898 GeneCards CYP2F1Gene location Human Chr Chromosome 19 human 1 Band19q13 2Start41 114 432 bp 1 End41 128 381 bp 1 Gene ontologyMolecular function iron ion binding oxygen binding arachidonic acid epoxygenase activity oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen metal ion binding monooxygenase activity heme binding oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen oxidoreductase activity aromatase activity steroid hydroxylase activityCellular component organelle membrane endoplasmic reticulum membrane intracellular membrane bounded organelle eyuxhum rangaehexnodphlasum isothphlasumBiological process epoxygenase P450 pathway trichloroethylene metabolic process xenobiotic metabolic process response to toxic substance organic acid metabolic process exogenous drug catabolic processSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez1572n aEnsemblENSG00000197446n aUniProtP24903n aRefSeq mRNA NM 000774n aRefSeq protein NP 000765n aLocation UCSC Chr 19 41 11 41 13 Mbn aPubMed search 2 n aWikidataView Edit Humanexnisminmhaskulisothokhrm P450 sungrwmthung CYP2F1 nncdepnexnismchnidmxnxxxksiciens sungmihnathisakhyinkarerngptikiryakarekidemaethbxlisumkhxngyachnidtang rwmipthungkarsngekhraahkhxelsetxrxl setxrxyd aelakrdikhmnchnidxun odyexnismehlanicaekhluxnthiekhasurangaehexnodphlasum aelwthukkratundwykluokhkhxrtikhxydcungcasamarthaesdngkhunsmbtikhxngexnismnnid inkrnikhxng CYP2F1 nnepnthithrabkndiwathahnathiinkardiihodrcienth dehydrogenate skaotl 3 methylindole sungepnsarphisphayinrangkaythiekidcakkrabwnkarhmkthripotefn ihxyuinrupthiimekidphis rwmipthungkaremaethbxilssarsbsetrtxun dwy echn aenfthalin aelaxithxksikhumarin ethoxycoumarin thngni CYP2F1 thuxepnsmachikkhxngklumexnismkhnadihykhxngisothokhrm P450 thimiyinkhwbkhumxyubnokhromosm 19q echnediywknexnismxuninskulyxykb CYP2A CYP2B aela CYP2F 3 duephim aekikhkhxmmxns miphaphaelasuxekiywkb CYP2F1 ephschkrrmisotokhrm P450 emaethbxlisumkhxngyaxangxing aekikh 1 0 1 1 1 2 GRCh38 Ensembl release 89 ENSG00000197446 Ensembl May 2017 Human PubMed Reference 3 0 3 1 Entrez Gene CYP2F1 cytochrome P450 family 2 subfamily F polypeptide 1 National Center for Biotechnology Information March 29 2018 CYP2F1 cytochrome P450 family 2 subfamily F member 1 Homo sapiens human U S National Library of Medicine khlngkhxmuleka ekbcak aehlngedim emux October 9 2017 subkhnemux April 11 2018 aehlngkhxmulxun aekikhtaaehnngcionm CYP2F1 khxngmnusy aelahnaephcaesdngkhxmulekiywkbyin CYP2F1 in UCSC Genome Browser Nhamburo PT Kimura S McBride OW aelakhna 1990 The human CYP2F gene subfamily identification of a cDNA encoding a new cytochrome P450 cDNA directed expression and chromosome mapping Biochemistry 29 23 5491 9 doi 10 1021 bi00475a012 PMID 1974816 CS1 maint uses authors parameter link Bale AE Mitchell AL Gonzalez FJ McBride OW 1991 Localization of CYP2F1 by multipoint linkage analysis and pulsed field gel electrophoresis Genomics 10 1 284 6 doi 10 1016 0888 7543 91 90514 F PMID 2045106 CS1 maint uses authors parameter link Trask B Fertitta A Christensen M aelakhna 1993 Fluorescence in situ hybridization mapping of human chromosome 19 cytogenetic band location of 540 cosmids and 70 genes or DNA markers Genomics 15 1 133 45 doi 10 1006 geno 1993 1021 PMID 8432525 CS1 maint uses authors parameter link Hoffman SM Fernandez Salguero P Gonzalez FJ Mohrenweiser HW 1996 Organization and evolution of the cytochrome P450 CYP2A 2B 2F subfamily gene cluster on human chromosome 19 J Mol Evol 41 6 894 900 doi 10 1007 bf00173169 PMID 8587134 CS1 maint uses authors parameter link Hakkola J Pasanen M Hukkanen J aelakhna 1996 Expression of xenobiotic metabolizing cytochrome P450 forms in human full term placenta Biochem Pharmacol 51 4 403 11 doi 10 1016 0006 2952 95 02184 1 PMID 8619884 CS1 maint uses authors parameter link Andersen MR Farin FM Omiecinski CJ 1998 Quantification of multiple human cytochrome P450 mRNA molecules using competitive reverse transcriptase PCR DNA Cell Biol 17 3 231 8 doi 10 1089 dna 1998 17 231 PMID 9539103 CS1 maint uses authors parameter link Lanza DL Code E Crespi CL aelakhna 1999 Specific dehydrogenation of 3 methylindole and epoxidation of naphthalene by recombinant human CYP2F1 expressed in lymphoblastoid cells Drug Metab Dispos 27 7 798 803 PMID 10383923 CS1 maint uses authors parameter link Chen N Whitehead SE Caillat AW aelakhna 2002 Identification and cross species comparisons of CYP2F subfamily genes in mammals Mutat Res 499 2 155 61 doi 10 1016 S0027 5107 01 00274 3 PMID 11827709 CS1 maint uses authors parameter link Strausberg RL Feingold EA Grouse LH aelakhna 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 CS1 maint uses authors parameter link Carr BA Wan J Hines RN Yost GS 2003 Characterization of the human lung CYP2F1 gene and identification of a novel lung specific binding motif J Biol Chem 278 18 15473 83 doi 10 1074 jbc M300319200 PMID 12598524 CS1 maint uses authors parameter link Tournel G Cauffiez C Billaut Laden I aelakhna 2007 Molecular analysis of the CYP2F1 gene identification of a frequent non functional allelic variant Mutat Res 617 1 2 79 89 doi 10 1016 j mrfmmm 2007 01 007 PMID 17327131 CS1 maint uses authors parameter link bthkhwamnirwbrwmkhxmulcakhxsmudaephthysastraehngchatixemrikn sungcdepnsatharnsmbtiekhathungcak https th wikipedia org w index php title CYP2F1 amp oldid 7558126, wikipedia, วิกิ หนังสือ, หนังสือ, ห้องสมุด,
