เตตราไซคลีน และไทกีไซคลีน (ยากลุ่มไกลซิลไซคลีน ซึ่งเป็นกลุ่มย่อยของเตตราไซคลีน) จะจับกับ A site บนไรโบโซม ทำให้อะมิโนเอซิลทีอาร์เอ็นเอน ไม่สามารถเข้าจับกับตำแหน่งดังกล่าวได้
พิวโรมัยซิน ซึ่งมีโครงสร้างคล้ายกับ ไทโรซินิลอะมิโนเอซิลทีอาร์เอ็นเอ จะเข้าจับกับตำแหน่ง A site บนไรโบโซมด้วยพันธะเพปไทด์ อย่างไรก็ตาม พิวโรมัยซินจะไม่ส่งผลต่อการย้ายตำแหน่งของไรโบโซม โดยหลังจากจับกับ A site แล้วยาดังกล่าวจะแยกตัวออกจากไรโบโซมอย่างรวดเร็ว ส่งผลให้การสังเคราะห์โปรตีนนั้นเข้าสู่ขั้นหยุดเร็วกว่าที่ควรจะเป็น
"Definition: protein synthesis inhibitor from Online Medical Dictionary".
"7.344 Antibiotics, Toxins, and Protein Engineering, Spring 2007". MIT OpenCourseWare.
Berg JM, Tymoczko JL, Stryer L. (2002). Eukaryotic Protein Synthesis Differs from Prokaryotic Protein Synthesis Primarily in Translation Initiation. Biochemistry. 5th Ed. W H Freeman.CS1 maint: uses authors parameter (link)
Swaney SM, Aoki H, Ganoza MC, Shinabarger DL (December 1998). "The Oxazolidinone Linezolid Inhibits Initiation of Protein Synthesis in Bacteria". Antimicrob. Agents Chemother. 42 (12): 3251–3255. PMC106030. PMID 9835522.CS1 maint: uses authors parameter (link)
Skripkin E, McConnell TS, DeVito J และคณะ (October 2008). "Rχ-01, a New Family of Oxazolidinones That Overcome Ribosome-Based Linezolid Resistance". Antimicrobial Agents and Chemotherapy. 52 (10): 3550–3557. doi:10.1128/AAC.01193-07. PMC2565890. PMID 18663023. Explicit use of et al. in: |authors= (help)CS1 maint: uses authors parameter (link)
Mehta, Roopal; Champney, W. Scott (2003). "Neomycin and Paromomycin Inhibit 30S Ribosomal Subunit Assembly in Staphylococcus aureus". Current Microbiology. 47 (3): 237–43. doi:10.1007/s00284-002-3945-9. PMID 14570276.
Slover CM, Rodvold KA, Danziger LH (June 2007). "Tigecycline: a novel broad-spectrum antimicrobial". Ann Pharmacother. 41 (6): 965–972. doi:10.1345/aph.1H543. PMID 17519296. สืบค้นเมื่อ 2009-12-19.CS1 maint: uses authors parameter (link)
↑ Flavio Guzmán (12/08/2008). "Protein synthesis inhibitors: aminoglycosides mechanism of action animation. Classification of agents". Pharmamotion. Check date values in: |date= (help)
↑ Protein synthesis inhibitors: macrolides mechanism of action animation. Classification of agents Pharmamotion. Author: Gary Kaiser. The Community College of Baltimore County. Retrieved on July 31, 2009
↑ Page 212 in: Title: Hugo and Russell's pharmaceutical microbiology Authors: William Barry Hugo, Stephen P. Denyer, Norman A. Hodges, Sean P. Gorman Edition: 7, illustrated Publisher: Wiley-Blackwell, 2004 ISBN0-632-06467-6 Length: 481 pages
"Geneticin". Thermo Fisher Scientific.
Wisteria Lane cases --> CLINDAMYCIN University of Michigan. Retrieved on July 31, 2009
Leonard JE, Grothaus CD, Taetle R (October 1988). "Ricin binding and protein synthesis inhibition in human hematopoietic cell lines". Blood. 72 (4): 1357–1363. PMID 3167211.CS1 maint: uses authors parameter (link)
Terao K, Uchiumi T, Endo Y, Ogata K (June 1988). "Ricin and alpha-sarcin alter the conformation of 60S ribosomal subunits at neighboring but different sites". Eur. J. Biochem. 174 (3): 459–463. doi:10.1111/j.1432-1033.1988.tb14120.x. PMID 3391162.CS1 maint: uses authors parameter (link)
↑ Menninger JR (1995). "Mechanism of inhibition of protein synthesis by macrolide and lincosamide antibiotics". J Basic Clin Physiol Pharmacol. 6 (3–4): 229–250. doi:10.1515/JBCPP.1995.6.3-4.229. PMID 8852269.
↑ Tenson T, Lovmar M, Ehrenberg M (July 2003). "The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome". J. Mol. Biol. 330 (5): 1005–1014. doi:10.1016/S0022-2836 (03) 00662-4 Check |doi= value (help). PMID 12860123.CS1 maint: uses authors parameter (link)
↑ Levinson, Warren (2008). Review of medical microbiology and immunology. New York: McGraw-Hill Medical. ISBN978-0-07-149620-9.
↑ Drugbank.ca > Showing drug card for Retapamulin (DB01256) Update Date: 2009-06-23
สิงหาคม 15, 2021
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irsin ybyngkartxsay odysngphlihekidkarepliynaeplngkhxngxarxarexnex khxnghnwyyxy 60 exskhxngirobosminyukharioxt 13 14 khnhyud aekikh aemkhokhrild 15 16 aela khlindamysin 15 16 thng 2 chnidyngmiklikkarxxkvththixuninkarxxkvththi thaiheppthidilthixarexnex peptidyl tRNA aeyktwxxkcakirobosmerwkwapkti phiwormysin sungmiokhrngsrangkhlaykb ithorsinilxamionexsilthixarexnex caekhacbkbtaaehnng A site bnirobosmdwyphnthaephpithd xyangirktam phiwormysincaimsngphltxkaryaytaaehnngkhxngirobosm odyhlngcakcbkb A site aelwyadngklawcaaeyktwxxkcakirobosmxyangrwderw sngphlihkarsngekhraahoprtinnnekhasukhnhyuderwkwathikhwrcaepn setrpotkramin epnyaptichiwnaxikchnidhnungthithaihkarsngekhraahsayphxlieppithdsinsuderwkwapkti 17 klikimcaephaa aekikh ertaphamulin 18 muphiorsin krdfusidikhtaaehnngxxkvththi aekikhyatxipniepnyathixxkvththiybyngkarsngekhraahoprtinodykarekhacbkbhnwyyxy 30 exskhxngirobosm xamioniklokhisd 17 ettraiskhlin 17 yatxipniepnyathixxkvththiybyngkarsngekhraahoprtinodykarekhacbkbhnwyyxy 50 exskhxngirobosm khlxaermefnikhxl 17 xiriothrmysin 17 khlindamysin 17 ilnioslid 17 klumxxksaosliidoxn ethliothrmysin 17 setrpotkramin 17 ertaphamulin 18 duephim aekikhkarsngekhraahoprtin karaeprrhsphnthukrrmkhxngesllophrkharioxtxangxing aekikh Definition protein synthesis inhibitor from Online Medical Dictionary 7 344 Antibiotics Toxins and Protein Engineering Spring 2007 MIT OpenCourseWare Berg JM Tymoczko JL Stryer L 2002 Eukaryotic Protein Synthesis Differs from Prokaryotic Protein Synthesis Primarily in Translation Initiation Biochemistry 5th Ed W H Freeman CS1 maint uses authors parameter link Swaney SM Aoki H Ganoza MC Shinabarger DL December 1998 The Oxazolidinone Linezolid Inhibits Initiation of Protein Synthesis in Bacteria Antimicrob Agents Chemother 42 12 3251 3255 PMC 106030 PMID 9835522 CS1 maint uses authors parameter link Skripkin E McConnell TS DeVito J aelakhna October 2008 Rx 01 a New Family of Oxazolidinones That Overcome Ribosome Based Linezolid Resistance Antimicrobial Agents and Chemotherapy 52 10 3550 3557 doi 10 1128 AAC 01193 07 PMC 2565890 PMID 18663023 Explicit use of et al in authors help CS1 maint uses authors parameter link Mehta Roopal Champney W Scott 2003 Neomycin and Paromomycin Inhibit 30S Ribosomal Subunit Assembly in Staphylococcus aureus Current Microbiology 47 3 237 43 doi 10 1007 s00284 002 3945 9 PMID 14570276 Slover CM Rodvold KA Danziger LH June 2007 Tigecycline a novel broad spectrum antimicrobial Ann Pharmacother 41 6 965 972 doi 10 1345 aph 1H543 PMID 17519296 subkhnemux 2009 12 19 CS1 maint uses authors parameter link 8 0 8 1 Flavio Guzman 12 08 2008 Protein synthesis inhibitors aminoglycosides mechanism of action animation Classification of agents Pharmamotion Check date values in date help 9 0 9 1 Protein synthesis inhibitors macrolides mechanism of action animation Classification of agents Pharmamotion Author Gary Kaiser The Community College of Baltimore County Retrieved on July 31 2009 10 0 10 1 Page 212 in Title Hugo and Russell s pharmaceutical microbiology Authors William Barry Hugo Stephen P Denyer Norman A Hodges Sean P Gorman Edition 7 illustrated Publisher Wiley Blackwell 2004 ISBN 0 632 06467 6 Length 481 pages Geneticin Thermo Fisher Scientific Wisteria Lane cases gt CLINDAMYCIN University of Michigan Retrieved on July 31 2009 Leonard JE Grothaus CD Taetle R October 1988 Ricin binding and protein synthesis inhibition in human hematopoietic cell lines Blood 72 4 1357 1363 PMID 3167211 CS1 maint uses authors parameter link Terao K Uchiumi T Endo Y Ogata K June 1988 Ricin and alpha sarcin alter the conformation of 60S ribosomal subunits at neighboring but different sites Eur J Biochem 174 3 459 463 doi 10 1111 j 1432 1033 1988 tb14120 x PMID 3391162 CS1 maint uses authors parameter link 15 0 15 1 Menninger JR 1995 Mechanism of inhibition of protein synthesis by macrolide and lincosamide antibiotics J Basic Clin Physiol Pharmacol 6 3 4 229 250 doi 10 1515 JBCPP 1995 6 3 4 229 PMID 8852269 16 0 16 1 Tenson T Lovmar M Ehrenberg M July 2003 The mechanism of action of macrolides lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome J Mol Biol 330 5 1005 1014 doi 10 1016 S0022 2836 03 00662 4 Check doi value help PMID 12860123 CS1 maint uses authors parameter link 17 0 17 1 17 2 17 3 17 4 17 5 17 6 17 7 17 8 Levinson Warren 2008 Review of medical microbiology and immunology New York McGraw Hill Medical ISBN 978 0 07 149620 9 18 0 18 1 Drugbank ca gt Showing drug card for Retapamulin DB01256 Update Date 2009 06 23ekhathungcak https th wikipedia org w index php title sarthiybyngkarsngekhraahoprtin amp oldid 9086191, wikipedia, วิกิ หนังสือ, หนังสือ, ห้องสมุด,
